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Healthcare

Pharmaceuticals

Every pharmaceutical industry is constantly faced with the challenge to produce and supply the best medicinal formulation (in any form) with complete adherence to Current Good Manufacturing Practices (CGMP). Handling of hazardous chemicals and maintaining a clean & controlled environment is a non-negotiable facet in any pharmaceutical plant. Nitrogen, is a key element in these plants as it acts as a blanketing agent around API’s (Active pharma ingredients) to prevent oxidation of sensitive ingredients being used to manufacture any kind of medicine. Furthermore, the containers used for storage purposes are also injected with Nitrogen before filling in the final product. Nitrogen is also being used as a safety medium against fire or explosions in areas handing materials that are flammable in nature.

Key Applications

API Blanketing

 Nitrogen protects active pharmaceutical ingredients from moisture and oxidation. This maintains chemical stability and ensures product integrity.

Packaging

Nitrogen is flushed into pharmaceutical packaging to maintain sterility.  It reduces oxygen exposure, enhancing shelf life and safety.

Cryogenic Freezing

Liquid nitrogen rapidly freezes biologicals and drugs for preservation.  It ensures molecular stability for storage and transport.

Challenges

Nitrogen
Need for extremely high-purity nitrogen
Oxidation
Risk of oxidation affecting drug stability
CGMP and regulatory requirements
Compliance with CGMP and regulatory requirements

Technical Data

Common Purity LevelPressureFlow
99.99% - 99.999%2-5 (Blanketing) 2-8(Purging) BargContact Us

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