In the pharmaceutical industry, it is always required to have a continuous supply of high-purity nitrogen for various uses such as in production, packaging, and preservation of drugs. The generation of nitrogen gas locally with PSA nitrogen generators has become common and a viable solution especially to the pharmaceutical companies. This method also assists in reducing costs while, at the same time, enhancing quality standards and the general organizational performance.
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The role played by Nitrogen in pharmaceuticals
Nitrogen is an inert gas which offers a protective layer to the products by avoiding any reaction with oxygen that could degrade most of the pharmaceutical products. Its applications include:
Packaging: Nitrogen is employed instead of oxygen in packing to enhance the shelf-life of drugs and to hinder moisture absorption.
Product Transfer: When transferring pharmaceutical ingredients, the use of nitrogen gas maintains a clean environment hence protecting the product from contamination.
Storage: Nitrogen is also used for storage of goods to keep them under an inert environment to prevent interaction with the surrounding environment
How PSA Nitrogen Generators Work
PSA Nitrogen generators are well known in the pharmaceutical industry as the source of nitrogen generated on a company’s premises. It works on the basis of Pressure Swing Adsorption that uses a molecular sieve to adsorb oxygen, carbon dioxide and moisture, while nitrogen is let through. This process creates nitrogen gas of very high purity, and the purity can be made to fit certain levels of purity.
Comparing Nitrogen Gas and Liquid Nitrogen
| Aspect | Nitrogen Gas | Liquid Nitrogen |
| State | Gaseous | Liquid |
| Purity Levels | High (Up to 99.999%) | High, but more variable |
| Storage Requirements | Low-pressure cylinders or generators | Cryogenic tanks |
| Cost | Lower operational costs | Higher due to cryogenic storage |
| Applications | Ideal for continuous use in processes and packaging | Used where extreme cooling is required (e.g., cryopreservation) |
| Safety | Generally Safer | Requires special handling |
Benefits of In-House Nitrogen Generation
Cost Savings: Saves on the cost of having to rely on outside suppliers, which means that transportation and delivery costs will be lower.
Quality Control: It guarantees the nitrogen purity that is required in the processes and also maintains the consistency of the same.
Efficiency: Ensures a constant flow of nitrogen and reduces the time spent on its replenishment, thus increasing production rates.
Safety: Minimizes the hazards involved in using and storing pressure vessels such as high-pressure gas cylinders or cryogenic liquids.
Using Nitrogen Generators in Pharma
The use of nitrogen generators in the pharmaceutical industry entails the generation of nitrogen with the right purity, flow rate and other considerations of the system. Current nitrogen generators are more sophisticated, efficient, easy-to-use and come with automation features to guarantee the best performance without frequent intervention.
Choose Absstem’s PSA Nitrogen Generators
Get Absstem’s PSA Nitrogen Generators for your pharmaceutical needs to get high purity nitrogen, save cost, and increase efficiency which is ideal for packaging, storage, and product transfer.
Conclusion
Thus, for pharmaceutical companies, nitrogen generation with the help of PSA Nitrogen Generators is one of the most effective and efficient solutions. This approach not only delivers high purity nitrogen required for numerous uses but also improves the operations’ effectiveness and reliability. Thus, as the industry progresses and looks for higher standards of nitrogen generation, the use of these technologies is expected to rise.
| Read More: – The Role of Nitrogen in 3D Metal Printing |
References
MICROBIOLOGICAL EVALUATION OF NITROGEN GAS IN PHARMACEUTICAL INDUSTRY
Microbiological Assessment of Compressed Gases in Pharmaceutical Facilities
